Zirconium oxide nanoparticles as an efficient catalyst for three-component synthesis of pyrazolo [1,2-a][1,2,4]triazole-1,3-diones derivatives

Abstract

An efficient and green protocol for the synthesis of pyrazolo[1,2-a][1,2,4]triazole-1,3-diones derivatives by one pot, three component coupling reaction of aromatic aldehyde, malononitrile, and 4-phenylurazole has been developed using ZrO2 nanoparticles (NPs) as the catalyst. The procedure is formed in high yields, short reaction time and an environmentally friendly specificity.