Stable reagents for the generation of N-centered radicals: Hydroamination of norbornene

Abstract

(Chemical Equation Presented) Radical transfer hydroaminations have been achieved with 3-aminated 1,4-cyclohexadienes rather than transition-metal reagents (see scheme; DTBP = di-tert-butylperoxide). These functionalized cyclohexadienes are efficient N-radical precursors. Moreover, they are stable and readily prepared, and radical generation occurs under neutral conditions. © 2005 Wiley-VCH Verlag GmbH & Co. KGaA.