Increased aquaporin I water channel expression in human brain tumours

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Abstract

Aquaporin I is a water channel protein. There was little aquaporin I immunoreactivity in normal brain parenchyma. In astrocytomas, aquaporin I was expressed in microvessel endothelia and neoplastic astrocytes. In metastatic carcinomas, aquaporin I was present in microvessel endothelia and reactive astrocytes. Aquaporin I may participate in the formation of brain tumour oedema. © 2002 Cancer Research UK.

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Saadoun, S., Papadopoulos, M. C., Davies, D. C., Bell, B. A., & Krishna, S. (2002). Increased aquaporin I water channel expression in human brain tumours. British Journal of Cancer, 87(6), 621–623. https://doi.org/10.1038/sj.bjc.6600512

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