Cutaneous Basal Cell Carcinoma with Lymph Node and Pulmonary Metastases

  • Wahl R
  • Cacchi C
  • Rübben A
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Abstract

Basal cell carcinoma (BCC) is the most common skin cancer. Metastatic BCC is an extraordinary rare finding observed in only 0.5% of all cases. Until the introduction of the small molecule hedgehog inhibitor vismodegib, patients with metastatic BCC were treated with chemotherapy, most frequently platinum-based with mixed responses to therapy. We present the case of a 55-year-old Caucasian man who suffered from BCC on his left arm with lymph node and pulmonary metastases. Sonic hedgehog blockade with vismodegib only induced a short remission, and the patient succumbed to the cancer.

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Wahl, R. U., Cacchi, C., & Rübben, A. (2018). Cutaneous Basal Cell Carcinoma with Lymph Node and Pulmonary Metastases. Case Reports in Oncological Medicine, 2018, 1–4. https://doi.org/10.1155/2018/3485326

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