Abstract
A 68-year-old man with sarcoidosis showed high 18F-FDG uptake in the mediastinal and hilar lymph nodes on 18F-FDG PET, suggesting active inflammation. 18F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of l-type amino acid transporter 1. 18F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on 18F-FDG PET.
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Watabe, T., Shimamoto, H., Naka, S., Kamiya, T., & Murakami, S. (2020). 18F-FBPA PET in Sarcoidosis: Comparison to Inflammation-Related Uptake on FDG PET. Clinical Nuclear Medicine, 45(11), 863–864. https://doi.org/10.1097/RLU.0000000000003274
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