Alpha-synuclein and Parkinson's disease: Implications from the screening of more than 1,900 patients

Abstract

G, g.10151G>A, and g.15986A>T) and the c.209G>A substitution corresponding to the p.A53T mutation. These results demonstrate that mutations in the α-synuclein gene are rare and suggest that other factors contribute to α-synuclein aggregation in the majority of PD patients. © 2005 Movement Disorder Society.