Isolation and Characterization of Phenolic Compounds from Magnoliae Cortex Produced in China

Abstract

A chemical examination of Magnoliae Cortex produced in China (Magnolia officinalis rehd.et wils., Magnoliaceae) has led to the isolation of eighteen new lignans and related compounds [four monoterpenyl-lignans: piperitylmagnolol (3), dipiperitylmagnolol (4), piperitylhonokiol (5) and bornylmagnolol (6); seven lignans: magnaldehydes B(8), C(9), magnolignans A(10), B(ll), C(12), D(13) and E(14); three norlignans: magnatriol B(16), magnaldehydes D(17) and E(18); and four dilignans: magnolignans F(19), G(20), H(21) and 1(22)], together with randainal (7), randaiol (15), sinapic aldehyde, syringaresinol, syringaresinol 4′-0-/J-D-glucopyranoside and 6 -0-methylhonokiol. Their structures were determined by the chemical and spectral methods. © 1991, The Pharmaceutical Society of Japan. All rights reserved.