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Short DNA Oligonucleotide as a Ag+Binding Detector

ACS Omega (2020) 5(44) 28565-28570
DOI: 10.1021/acsomega.0c03372
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Abstract

Ag+ has been known to mediate several natural metallo-base pairs. Based on the unique structural information of a short 8-mer DNA strand (5′-GCACGCGC-3′) induced by Ag+, we constructed several fluorescent DNA beacons for the detection of Ag+ according to the increase in the fluorescence emission on Ag+ binding. This Ag+ detection assay is quick, sensitive, and easy to adapt and can function in a wide range of temperatures from 5 to 65 °C.

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Shen, F., Mao, S., Mathivanan, J., Wu, Y., Chandrasekaran, A. R., Liu, H., … Sheng, J. (2020). Short DNA Oligonucleotide as a Ag+Binding Detector. ACS Omega, 5(44), 28565–28570. https://doi.org/10.1021/acsomega.0c03372

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