Do Casiopeinas® Prevent cancer disease by acting as antiradicals? A chemical reactivity study applying density functional theory

Abstract

The main goal of this investigation is to study the possible mechanisms of Casiopeinas® as anticancer agents. Electrodonating (χ -) and electroaccepting (χ +) electronegativity were calculated applying Density Functional Theory. Two different anticancer mechanisms of Casiopeínas® are proposed. There might be antiradical molecules preventing the formation of cancer cells or these molecules could reduce the amount of GSH and as a result over-produce free radicals, increasing the oxidative stress which in turn kills the cancer cells. © 2012, Sociedad Química de México.