Compliance-adjusted Intervention Effects in Survival Data

Abstract

Survival data are most frequently analyzed by the intention-to-treat principle. However, presenting a compliance-adjusted analysis alongside the primary analysis can provide an insight into the effect of the treatment for those individuals actually complying with their randomized intervention. There are a number of methods for this type of analysis. Loeys and Goetghebeur (2003) use proportional hazards techniques to provide an estimate of the treatment effect for compliers when compliance is measured on an all-or-nothing scale. This methodology is here made available through a new Stata command, stcomply.