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Interleukin-28B polymorphisms and response of chronic hepatitis C patients from Indonesia to pegylated interferon/ribavirin treatment

Journal of Clinical Microbiology (2014) 52(6) 2193-2195
DOI: 10.1128/JCM.00768-14
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Abstract

This study demonstrated that Indonesian patients with chronic hepatitis C (mostly ethnic Java people) mostly were infected with hepatitis C virus (HCV) genotype 1; however, they carried mainly the major genotypes of interleukin 28B (IL-28B) single nucleotide polymorphisms (SNPs) (rs12979860 CC, rs11881222 TT, rs8103142 AA, and rs8099917 TT), and they mostly achieved sustained virological responses to pegylated interferon/ribavirin treatment. Copyright © 2014, American Society for Microbiology. All Rights Reserved.

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Juniastuti, J., Wibowo, B. P., Wibawa, I. D. N., Utsumi, T., Mustika, S., Amin, M., … Lusida, M. I. (2014). Interleukin-28B polymorphisms and response of chronic hepatitis C patients from Indonesia to pegylated interferon/ribavirin treatment. Journal of Clinical Microbiology, 52(6), 2193–2195. https://doi.org/10.1128/JCM.00768-14

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