The double-edge sword effect of anti-CD73 cancer therapy

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Abstract

We and others have identified CD73 as a new cancer target. I hereafter discuss that targeted blockade of CD73 has the effect of a "double-edge sword," able on the one hand to rescue endogenous adaptive anti-tumor immune responses, and on the other hand, inhibit the metastatic potential of tumor cells. © 2012 Landes Bioscience.

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Stagg, J. (2012). The double-edge sword effect of anti-CD73 cancer therapy. OncoImmunology. https://doi.org/10.4161/onci.1.2.18101

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