Sleep disordered breathing is associated with appropriate implantable cardioverter defibrillator therapy in congestive heart failure patients

Abstract

Background: Implantable cardioverter defibrillators (ICDs) are increasingly employed in patients affected by congestive heart failure (CHF) and sleep disordered breathing (SDB) is frequent in this population. Hypothesis: To investigate SDB prevalence and influence on appropriate ICD discharges in CHF patients. Methods: A total of 22 consecutive ICDpatients with systolic CHF (left ventricular ejection fraction [LVEF]<45%) were studied by polysomnography. Results: A total of 17 (77.2%) showed SDB (apnea-hypopnea index [AHI]-10 events/hour). After controlling for LVEF and New York Heart Association (NYHA) class, AHI and severity of hypoxia during sleep results correlated to appropriate ICD discharges (r = 0.718; P < .001, r = -0.619; P = .003, respectively). Conclusions: Sleep disordered breathing is frequent in ICDrecipients due to left systolic ventricular dysfunction and may increase the risk of ventricular arrhythmia and appropriate ICD discharges. © 2010 Wiley Periodicals, Inc.