A synthetic study on the preparation of triarylmethanes

Abstract

A number of triarylmethanes were prepared, the majority of which are new. One of the aryl groups is a naphthol, 1,3,5-trimethoxybenzene, or resorcinol, or an indole, pyrrole or pyridine ring. Three synthetic routes are described: (1) reaction of a benzhydrol with an electron-rich aromatic compound; (2) direct condensation of benzaldehyde or hydroxybenzaldehydes, with N,N-dimethylaniline or its derivatives and 2-naphthol; and (3) displacement of benzotriazole in benzotriazolyl derivatives by Grignard reagent according to our recently developed benzotriazole methodology. © 1994.