Miniaturized detection devices powered by various heaters: A quick review under the background of water-borne disease epidemics

Abstract

With the progress of society and the development of productivity, the problem of water pollution and water shortage caused by water pollution is becoming more and more serious. Water-borne diseases caused by pathogenic microorganisms also bring great harm to human beings and other life forms. These microorganisms include bacteria, viruses, protozoa, and parasitic pathogens. Traditional detection methods are time-consuming and costly, and can’t meet the needs of water resource detection. Therefore, there is an urgent need for accurate, rapid, specific, and portable detection equipment for detecting pathogenic microorganisms in water. We analyzed and sorted out the detection methods and detection equipment for detecting pathogenic microorganisms that cause water-borne diseases, summarized these detection methods and detection equipment, and analyzed the advantages and disadvantages of these detection methods. We reasonably concluded that a good detection method for pathogenic microorganisms in water should have the advantages of low cost, low energy consumption, simple operation, strong specificity, and high portability, which can more easily meet the needs of the water quality detection field. Multifunctional small nucleic acid detection devices have been reported for decades, which reduce the reaction time of nucleic acid amplification from hours to minutes, and these miniaturized devices based on nucleic acid amplification are not only highly specific but also low cost, which is very suitable for resource-limited environments.