Efeitos colaterais cutâneos de quimioterapia com taxanos. O ponto de vista do dermatologista

Abstract

Chemotherapy with taxanes has recently become part of the treatment for many advanced neoplastic diseases, specially breast and lung cancer. Their main noncutaneous adverse reactions include neutropenia and mucositis, which eventually lead to drug discontinuation. Cutaneous adverse reactions are frequent and significantly interfere with the patient's quality of life. Treatments are poorly effective, but special recommendations may improve symptoms and prevent relapses requiring drug rechallenge. © 2011 by Anais Brasileiros de Dermatologia.