The heart is one of the least regenerative organs in the human body; adult cardiac myocytes divide at extremely low frequency. Therefore, meaningful induction of cardiac regeneration requires in-depth understanding of myocyte cell-cycle control. Recent insights into how myocytes can be coaxed into duplicating in vivo might inform emerging therapeutics.
CITATION STYLE
Jain, R., Poleshko, A., & Epstein, J. A. (2018, May 18). Beating the odds: Programming proliferation in the mammalian heart. Genome Medicine. BioMed Central Ltd. https://doi.org/10.1186/s13073-018-0550-5
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