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Oxidative Stress Changes Induced by Methotrexate on Parotid Gland Structure of Adult Male Albino Rat: Can Vitamin C Ameliorate These Changes?

  • DOAA MOHAMMED YOUSEF, M.D. S
  • AL-SEMEH, M.D. A
The Medical Journal of Cairo University (2019) 87(June) 2555-2565
DOI: 10.21608/mjcu.2019.54869
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Abstract

Background: Methotrexate (MTX) is a cytotoxic chemo-therapeutic agent for several malignancies and various inflam-matory diseases. Salivary dysfunction is one of MTX muco-toxic effects. Vitamin C (vit. C) scavenges the oxidative molecules and free radicals since it is a potent hydrophilic antioxidant.

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DOAA MOHAMMED YOUSEF, M.D., S. S. A. E.-F., M. D., & AL-SEMEH, M.D., A. E. (2019). Oxidative Stress Changes Induced by Methotrexate on Parotid Gland Structure of Adult Male Albino Rat: Can Vitamin C Ameliorate These Changes? The Medical Journal of Cairo University, 87(June), 2555–2565. https://doi.org/10.21608/mjcu.2019.54869

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