Growth Inhibition of Glucose-Grown Cariogenic and Other Streptococci by Saccharin in vitro

Abstract

Sodium saccharin in concentrations from 0.02 to 20.00 mg/ml inhibits the in vitro growth of glucose-grown cariogenic and other streptococci and suppresses, esp. at the higher concentration ränge, the fermentative acid production of these microorganisms to acid levels much lower than the critical pH of 5.5. These observations indicate a possible caries antagonism by saccharin. © 1977, Verlag der Zeitschrift für Naturforschung. All rights reserved.