Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury

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Abstract

Lymphocytes play an important role during ischemia-reperfusion injury (IRI). Lai et al. have demonstrated, for the first time, an increase in kidney lymphocytes 1 hour after IRI, a newly identified kidney lymphocyte reservoir, and have confirmed the pathogenic role of lymphocytes by manipulating the sphingosine-1-phosphate (SIP)-sphingosine-1-phosphate type 1 (S1P1) receptor pathway. © 2007 International Society of Nephrology.

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Gandolfo, M. T., & Rabb, H. (2007). Very early alloantigen-independent trafficking of lymphocytes during ischemic acute kidney injury. Kidney International. Nature Publishing Group. https://doi.org/10.1038/sj.ki.5002285

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