PhI(OAc)2 mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives

Abstract

A phenyliododiacetate (PhI(OAc)2) mediated an efficient and novel protocol for the Knoevenagel reaction has been successfully accomplished. A base free, simple and straightforward method afforded wide substrate scope and good functional group tolerance, having high yields (80–92%) under environmentally benign and mild reaction conditions.