Use of Testosterone-Lowering Medication in Patients With Intellectual Disabilities and Problematic Sexual Behaviour: A Case Series

Abstract

Background: Testosterone-lowering medication (TLM) is used in severe cases of paraphilic disorders and problematic sexual behaviour, but its use in patients with intellectual disability is not well characterised. Method: A nationwide survey identified five male patients with intellectual disability who had received TLM in specialised outpatient clinics. Results: Four patients showed reduced problematic sexual behaviour during treatment; three relapsed after discontinuation. Adverse effects included osteoporosis, hypertension, depression and suppressed sexual development. Monitoring and access varied regionally. Conclusions: TLM may be effective in selected patients with intellectual disability but requires careful monitoring and ethical oversight.