Peer review in clinical pharmacology using the 8-D assessment

Abstract

The requirement for editors of clinical pharmacology journals to maintain an overview of the peer review process for manuscripts submitted can be facilitated by use of the 8-D Assessment. The 8-D Assessment comprises peer review criteria to determine if the:1. Design of the study, 2. Diagno-ses employed, 3. Drug molecules involved, 4. Dosages applied, 5. Data collected, 6. Dis-cussion of the fndings, 7. Deductions made, and 8. Documentation are in accord with the objectives of the study and meet the requirements of evidence-based medicine. This tool, although easy to apply, requires a high level of clinical pharmacology expertise, especially in the felds of drug disposition, pharmacokinet-ics, and drug action.