Essential benign fructosuria

Abstract

A case of essential benign fructosuria in an I -year-old Jewish girl is described. Both hyperglycaemia induced by administration of dextrose or glucagon and hypoglycaemia induced by administration of insulin or tolbutamide affected the duration and/or the amount of fructose excreted in the urine after a fructose load. The patient was able to metabolize up to 50 mg. of fructose per minute. Any amount in excess was excreted in the urine. These findings are discussed in the light of the enzymatic disturbances invoked in this metabolic disorder.