Non-derivatized glycan analysis by reverse phase liquid chromatography and ion mobility-mass spectrometry

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Abstract

A simple method for the analysis of non-derivatized glycans using a reverse phase column on a liquid chromatography-ion mobility-mass spectrometry (LC-IM-MS) instrument. The methodology supports both glycomic and proteomic work flows without the necessity of switching columns.

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Lareau, N. M., May, J. C., & McLean, J. A. (2015). Non-derivatized glycan analysis by reverse phase liquid chromatography and ion mobility-mass spectrometry. Analyst, 140(10), 3335–3338. https://doi.org/10.1039/c5an00152h

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