Long-Term Effects Of Combined Treatment With Memantine And Donepezil On Alzheimer's Disease Patients: 72-Week Study

  • Wake R
  • Araki T
  • Miyaoka T
  • et al.
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Abstract

Objective: In this study, we evaluated the long-term effects of memantine on cognitive function, BPSD, and the care burden in patients with moderate to severe Alzheimer's disease (AD) for 72 weeks. Further, we examined the association between the long-term effects of memantine and brain blood flow using near-infrared spectroscopy (NIRS).

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Wake, R., Araki, T., Miyaoka, T., Nagahama, M., Furuya, M., Hayashida, M., … Horiguchi, J. (2018). Long-Term Effects Of Combined Treatment With Memantine And Donepezil On Alzheimer’s Disease Patients: 72-Week Study. Neuropsychiatry, 08(03). https://doi.org/10.4172/neuropsychiatry.1000421

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