Abstract
Natural killer (NK) cell activity was found decreased (mean value: 27.5%) in peripheral blood lymphocytes from 59 untreated patients with malignant lymphoma, when compared to 112 healthy subjects (46.3%) and to 75 cancer patients with nonlymphoid tumors (43.7%) (P > 0.001). NK cell values were similar in patients with Hodgkin's disease (25.5%) and with non‐Hodgkin's lymphoma (28.2%). Decreased NK cell activity was not correlated with age, lymphoma extension or leukocyte counts. A physiological role for NK cells in the immune surveillance against lymphoid neoplasias is discussed. Copyright © 1982 American Cancer Society
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CITATION STYLE
Tursz, T., Dokhelar, M. ‐C, Lipinski, M., & Amiel, J. ‐L. (1982). Low natural killer cell activity in patients with malignant lymphoma. Cancer, 50(11), 2333–2335. https://doi.org/10.1002/1097-0142(19821201)50:11<2333::AID-CNCR2820501119>3.0.CO;2-W
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