Osteorradionecrosis como secuela de la radioterapia

Abstract

The osteoradionecrosis is one of the most serious complications of head and neck radiation therapy, is described as a disturbance in which bone is bone desvitalización with hypovascularity, hypocellularity (fibroblasts, osteoclasts, osteogenic cells undifferentiated), and hypoxia local tissue. Occurs spontaneously or in response of a wound when the patient is subjected to irradiation doses above 60 G and especially with concomitant chemotherapy. The bone can not respond properly after local trauma such as dental extractions, biopsies to rule out recurrence, periodontal diseases. Predisposing factors include the radiation absorbed dose, fractionation, delivery modality, or mental state. After symptoms appear but sometimes trigger symptoms appear without prior approval. This can be reduced through early assessment, treatment and cure intraoral, before the start of tissue regeneration. For the treatment are taken into account antibiotics, hyperbaric oxygen therapy and surgical techniques, including hemimandibulectomy and placement of the graft in each case.