Enhancing anti-melanoma immunity by electrochemotherapy and in vivo dendritic-cell activation

Abstract

Combining electrochemotherapy with dendritic cell-based immunotherapy is a promising strategy against human metastatic melanoma that deserves to be clinically assessed. While electrochemotherapy induces a rapid regression of metastases, immunotherapy generates systemic anticancer immunity, contributes to eradicate the tumor and maintains an immunological memory to control relapse. © 2012 Landes Bioscience.