Design and Synthesis of Metastable 4H-3,1-Benzoxazin-4-one and 3-aminoquinazoline-4(3H)-one for Detecting Cations in Water Samples and Agricultural Crops

Abstract

The behaviour of 2-benzyl-4H-3,1-benzoxazin-4-one towards nitrogen nucleophiles namely, amino acids, aromatic amines, sodium azide, and secondary amines has been investigated. Also the reaction of 3-amino-2-benzylquinazolin-4(3H)-one and 2-[2-benzyl-4-oxoquinazolin-3(4H)-yl]acetohydrazide with carbon electrophiles has been discussed. As well as The novel synthesized compounds were evaluated as chemosensor for detecting formyl, carbonyl group and revealed high-selectivity and specificity to detect metals ions in water samples and, agricultural crops. Qualitative and quantitative assays indicated appreciable selectivity of novel compounds 13 and 15 as a chemo sensor for Optical detection of Hg2+and Cr2+ respectively.