A case report of placental mesenchymal dysplasia A rare case of a genetically normal fetus with severe intrauterine growth restriction

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Abstract

Rationale: We report a rare case of a pregnant woman with placental mesenchymal dysplasia (PMD) and intrauterine growth restriction (IUGR) with a genetically normal fetus. Patient concerns: A 42-year-old woman Gravida I, Para I with pre-existent uncontrolled hypertension and uterine polyfibromatosis present at 30 weeks of gestation for diminished fetal activity during the last 2 days. Diagnosis: Placentalmesenchymal dysplasia associated with intrauterine growth restriction, hypertension, and uterinepolyfibromatosis. Intervention: A live male infant was delivered by emergency caesarean section. Outcomes: The infant, weighing 700g, died 4 days after birth due to a massive intracerebral hemorrhage. Lessons: A careful examination should be done at every ultrasound in case of a fetus with IUGR to exclude some rare cases of placental pathologies. PMD can be a rare cause of IUGR with a genetically normal fetus.

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Doroftei, B., Neculai-Valeanu, S., Simionescu, G., Grab, D., Plopa, N., Anton, E., & Maftei, R. (2019). A case report of placental mesenchymal dysplasia A rare case of a genetically normal fetus with severe intrauterine growth restriction. Medicine (United States), 98(8). https://doi.org/10.1097/MD.0000000000014554

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