Effects of Resistance Exercise to Failure Versus Nonfailure on Appetite, Hormones, and Energy Intake in Young Healthy Males

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Abstract

This study examined how resistance exercise (RE) volume, a potential key factor in appetite regulation, influences subjective appetite, gut appetite hormones, and energy intake. Eighteen males (aged 21–27 years) completed failure RE (FRE; three sets of failure reps at 70% (at 1 RM), non-FRE (NFRE; 3 × 7 reps at 70% 1 RM), and control (CON) trials. Appetite and acyl-ghrelin, peptide YY, lactate, and glucose were measured pre-and postexercise 0–90 min. Ad libitum meal was provided after exercise. Participants recorded energy intake for the day before, the day of, and the day after each session. The incremental area under the curve (iAUC) for acyl-ghrelin (AG) in the FRE and NFRE were significantly lower than in the CON (p NFRE > CON; p

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Cheng, H. C., Liu, H. W., Kuo, Y. C., Yu, P. H., Yeh, K. T., & Hsieh, C. H. (2026). Effects of Resistance Exercise to Failure Versus Nonfailure on Appetite, Hormones, and Energy Intake in Young Healthy Males. International Journal of Sport Nutrition and Exercise Metabolism, 36(4), 397–407. https://doi.org/10.1123/ijsnem.2025-0094

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