Water-soluble constituents of anise: New glucosides of anethole glycol and its related compounds

Abstract

From the water-soluble portion of the methanolic extract of the fruit of anise (Pimpinella anisum L.), which has been used as a spice and medicine since antiquity, twelve new and five known glucosides of phenylpropanoids, including four stereoisomers of anethole glycol 2′-O-β-D-glucopyranoside and four stereoisomers of 1′-(4-hydroxyphenyl)propane-1′,2′-diol 2′-O-β-D-glucopyranoside were isolated together with anethole glycols and guaiacyl glycerol. The structures of the new compounds were clarified by spectral investigation. © 2002 Pharmaceutical Society of Japan.