Electrical contacting of glucose oxidase in a redox-active rotaxane configuration

Abstract

Shuttle of electrons: A redox-active bisbipyridinium cyclophane stoppered by the enzyme glucose oxidase (GOx) in a rotaxane configuration on a molecular wire linked to a gold electrode (see picture) leads to the effective electrical contacting of the biocatalyst that oxidizes glucose at -0.4 V (versus saturated calomel electrode).