Abstract
A systematic review of randomized and observational studies from 2013 to 2023 demonstrated that antiviral preemptive therapy started at cytomegalovirus viral load thresholds between 2 and 3 log10 IU/mL was associated with similar cytomegalovirus disease rates. Thus, viral thresholds in this range appear to effectively protect patients not receiving prophylaxis.
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Sadowska-Klasa, A., Leisenring, W. M., Limaye, A. P., & Boeckh, M. (2024). Cytomegalovirus Viral Load Threshold to Guide Preemptive Therapy in Hematopoietic Cell Transplant Recipients: Correlation With Cytomegalovirus Disease. Journal of Infectious Diseases, 229(5), 1435–1439. https://doi.org/10.1093/infdis/jiad386
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