Accurate localization of functionally meaningful Regions of Interests (ROIs) from fMRI data is critically important to functional brain imaging. A variety of established approaches such as General Linear Model (GLM) have been widely used in the community. How to determine the optimal location and size of an fMRI-derived ROI, however, remains an open, challenging problem. This paper presents a novel individualized optimization algorithm that simultaneously optimizes the locations and sizes of fMRI-derived ROIs by maximizing the coherences of their functional interaction patterns with respect to the block-based paradigm. As an alternative ROI optimization approach using functional interaction patterns, the algorithm was applied on a working memory task-based fMRI dataset and the experimental results are promising.
CITATION STYLE
Deng, F., Zhu, D., & Liu, T. (2012). Optimization of fMRI-derived ROIs based on coherent functional interaction patterns. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 7512 LNCS, pp. 214–222). Springer Verlag. https://doi.org/10.1007/978-3-642-33454-2_27
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