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In vitro study of Candida tropicalis isolates exhibiting paradoxical growth in the presence of high concentrations of caspofungin

Antimicrobial Agents and Chemotherapy (2007) 51(12) 4474-4476
DOI: 10.1128/AAC.00880-07
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Abstract

Paradoxical growth was noted in RPMI 1640 and antibiotic medium 3 in the case of 14 and 1 of 15 Candida tropicalis strains, respectively, at a caspofungin concentration of 12.5 μg/ml using minimum fungicidal concentration tests. Time-kill assays showed that against isolates killed at lower concentrations, caspofungin at a concentration of 12.5 μg/ml was only fungistatic. Copyright © 2007, American Society for Microbiology. All Rights Reserved.

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Sóczó, G., Kardos, G., Varga, I., Kelentey, B., Gesztelyi, R., & Majoros, L. (2007). In vitro study of Candida tropicalis isolates exhibiting paradoxical growth in the presence of high concentrations of caspofungin. Antimicrobial Agents and Chemotherapy, 51(12), 4474–4476. https://doi.org/10.1128/AAC.00880-07

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