Apicomplexan gliding motility and host cell invasion: Overhauling the motor model

Abstract

A unique actomyosin motor powers both host cell invasion and locomotion of apicomplexan invasive stages. This article integrates a revised model of some of the recent advances in our understanding of the components and the overall molecular architecture of this intriguing motion system. Many questions remain, however, regarding the dynamics and regulation of the motor complex.