Review on Bio-inspired Materials with Nanotechnology Applications in Medical Devices

Abstract

Nano-biomimetic material is a multidisciplinary field emerging gradually with the development of micro-nano technology, which covers many fields such as materials science, nanotechnology, biology, artificial intelligence, medicine. The existence of micro-nano technology has led to major breakthroughs in many aspects of these fields, giving people possible opportunity to design and modify new drugs, organ-on-chips and so on at the micron or nanometer scale. At present, nano-biomimetic materials have played an important role in drug development and toxicity testing, self-healing of biomedical materials and flexible nanorobots. For example, hydrogels performance has been improved by the addition of some specific nanomaterials. The future research direction of nanoscale-hydrogel binding materials is still under search now. Another new product - Organ-on-chip is also highly dependent on nanotechnology. Three kinds of representative organ-on-chip, heart-on-chip, kidney-on-chip and lung-on-chip are now been supported by microfluidic technology. Their applications and prospect in medicines are hot topics at present. Furthermore, the principle of how nanomaterials improved (Ion-exchange polymer-metal composite) IPMC's characters and its application in capsule robot field and artificial muscle field are under discussion. But to people's expectation, IPMC still has a good prospect. This research looks forward to the application of biological nanotechnology in more fields.