Domestic pig unlikely reservoir for MERS-COV

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Abstract

We tested the suitability of the domestic pig as a model for Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Inoculation did not cause disease, but a low level of virus replication, shedding, and seroconversion were observed. Pigs do not recapitulate human MERS-CoV and are unlikely to constitute a reservoir in nature.

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De Wit, E., Feldmann, F., Horne, E., Martellaro, C., Haddock, E., Bushmaker, T., … Feldmann, H. (2017). Domestic pig unlikely reservoir for MERS-COV. Emerging Infectious Diseases, 23(6), 985–988. https://doi.org/10.3201/eid2306.170096

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