Advantages of isolated application of fibrin glue over suture in preservation of second-grade spleen lesion

Abstract

Objectives: The aim of this procedure was to assess the safety and efficiency of glue application in the treatmentof lienal second-degree lesions, compared with traditional suture method of treatment. Background: The spleen is the most frequently injured intra-abdominal structure regardless of injury mechanisms. Fibrin glue is a useful bio-adhesive forsafe and effi cient treatment of diffuse parenchymatous spleen haemorrhages. Methods: Seventy dogs under intravenous anaesthesia were subdued to spleen incision in length of 5 cm and depth of 2 cm. Forty animals from the experimental group were treated with fi brin glue preservation, and 30 animals from the control group were treated with suture. Removed spleens were histologically analyzed. No animal was sacrifi ced. Results: The application of fi brin glue allowed reparation to be accomplished in all cases. The effectiveness of primary repair was registered in 95 %, with only 5 % of cases requiring an application of fi brin omentoplasty. Secondary bleeding was registered only in 1 (2.5 %) case. Preservationwith suture is primarily effective only in 40 %, requires additional repair in 23 %, and even 37 % of cases are not feasible. This method is characterized by mortality of 21 %, secondary haemorrhage (32 %), appearance of focal necrosis (42 %)and abscess (11 %). Conclusions: Application of FG is a method of choice in cases of second-degree transcapsular spleen lesions and it has a considerable advantage over suture.