IMPACT OF FAMILY HISTORY IN GLYCEMIC CONTROL AMONG TYPE-2 DIABETES MELLITUS PATIENTS IN ASEER DIABETIC CENTER

Abstract

There is a significant increase in the incidence and prevalence of Diabetes Mellitus (DM) worldwide and in the Kingdom of Saudi Arabia (KSA). Various studies have been shown the relevance of genetic factor in the onset of type-2 diabetes mellitus (T2DM). In this view the study has been conducted to find the correlation between family history and glycemic control among the T2DM patients in Aseer Diabetic Center (ADC), Abha KSA. This is a cross sectional retrospective study. A total of 343 patient's medical records were accessed to evaluate the role of family history in glycemic control. For the purpose of the study patients were randomly selected and divided into four groups (I-without family history; II-with first degree family history; III-with second degree family history and IV-with both first and second degree family history). The HbA1c value was considered as primary outcome measure in each group. In addition to this other factors such as age, duration of DM, BMI (Body Mass Index) were also studied. Among this study population, about 54.81 % of patients had positive 1 st degree family history. The mean age for patients without family history is 62.19 (± 9.29) yrs and 59.98 (± 10.39) for patients with family history, which shows that occurring of DM is early in positive family history groups. The HbA1c value in patients without family history and with family history in either sex is not significant (p < 0.39). In our study, HbA1c levels show no significant difference between patients with and without family history. In conclusion the family history plays no significant role in glycemic control in T2DM patients in ADC.