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MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila

Cell Reports (2018) 23(13) 3776-3786
DOI: 10.1016/j.celrep.2018.05.078
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Abstract

To examine the role of microRNAs in sleep, Goodwin et al. screened a Drosophila microRNA sponge library, identifying 25 microRNAs that regulate sleep. The majority of these were from families well conserved in vertebrates. Let-7, a strong hit from the screen, has both adult and developmental roles.

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Goodwin, P. R., Meng, A., Moore, J., Hobin, M., Fulga, T. A., Van Vactor, D., & Griffith, L. C. (2018). MicroRNAs Regulate Sleep and Sleep Homeostasis in Drosophila. Cell Reports, 23(13), 3776–3786. https://doi.org/10.1016/j.celrep.2018.05.078

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