Oral microbiome

Abstract

This study aimed to analyze the characteristics of the oral microbiome in dental caries and inflammatory periodontal diseases based on available data in the modern literature. This article is based on the analysis of materials from international and Russian studies in the PubMed, CyberLeninka, and MedLine databases over the past 15 years. An imbalance in the oral microbiome can develop dental caries and periodontal diseases. Normally, the oral microbiome contains Firmicutes, Proteobacteria, Actinobacteria, Bacteroides, Fusobacterium, and Spirochetes. With dental caries, S. mutans, Atopobium, Propionibacterium, and Lactobacillus are determined. The presence of Veillonella, Porphyromonas gingivalis, Tannerella forsythia, Aggregatibacter actinomycetemcomitans, Treponema, and Prevotella in the oral microbiome is associated with periodontal disease. The oral microbiome database comprises comprehensive data that describe bacterial species and the 16S rRNA that define the set of oral microbes. The microbiome is influenced by local and general factors.