Cannabis y psicopatología comorbida

Abstract

The cannabis, illegal drug more used by the youths and one of those which earlier is begun to consume, it presents frequently comorbid psychopathology. Consuming cannabis are presented psychotic episodes in lucid conscience with few formal alterations of the thought, maniac feature affectivity, hostile behavior, short duration and reappearance always preceded by its consumption, However, it continues in discussion if the cannabis is the detonative of the psychosis or a form of self-medication of a primary psychotic disorder. The reiterated use of cannabis from very young, above all in subject genetically vulnerable, cause schizophrenias whose first episode is presented after a yr of THC consumption, generally before 18 years, with more positive symptoms and less negative than schizophrenics not users, with worse response to the antipsychotic and more relapses in the following 15 years, This seems be due to the fact that in the schizophrenics is produced an similar alteration of the endogenous cannabinoid system at the originated by the cannabis-related poisoning in healthy subjects. To consume high cannabis dose during much time leads to a passiveness and nonchalance state characterized by generalized dysfunction of the cognitives capacities and of the interpersonal and social abilities (call amotivational syndrome) of the that are begun to have neuropsychological, morphologic and functional evidences.