Polymorphisms in BER and NER pathway genes: Effects on micronucleus frequencies among vinyl chloride-exposed workers in northern China

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Abstract

In this study, a group of 317 workers occupationally exposed to vinyl chloride monomer and 166 normal, unexposed referents in Shandong province (Northern China) were examined for chromosomal damage in peripheral lymphocytes using the cytokinesis-blocked micronucleus (CB-MN) assay. The exposure group (3.47. ±. 2.65)‰ showed higher micronucleus frequency than the unexposed workers (2.51. ±. 1.96)‰ (. P

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Wang, Q., Tan, H. shan, Zhang, F., Sun, Y., Feng, N. nan, Zhou, L. fang, … Xia, Z. lin. (2013). Polymorphisms in BER and NER pathway genes: Effects on micronucleus frequencies among vinyl chloride-exposed workers in northern China. Mutation Research - Genetic Toxicology and Environmental Mutagenesis, 754(1–2), 7–14. https://doi.org/10.1016/j.mrgentox.2013.03.007

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