Pleomorphic xanthoastrocytoma with malignant transformation and multiple recurrences in an Iranian girl.

Abstract

Pleomorphic xanthoastrocytoma (PXA) is a rare astrocytic tumour of the brain. Some PXAs are accompanied by anaplastic features and are difficult to manage because of frequent recurrences that lead to early death. Well-documented cases of malignant transformation in PXA and of anaplastic PXA are rare in the literature. The authors report a case of PXA with malignant transformation in the right temporo occipital lobe in a 13-year-old Iranian girl.