Corneal thickness in ocular hypertension, primary open-angle glaucoma, and normal tension glaucoma

Abstract

Objectives: To determine the effect of central corneal thickness (CCT) on the measurement of intraocular pressure (lOP) and on the resultant reclassification of patients as having primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHT). Methods: Intraocular pressure (Goldmann applanation tonomety) and CCT (ultrasound pachymetry) were measured in 22 patients with NTG, 49 with POAG, 44 with OHT and in 18 control subjects. The CCT was used to obtain a corrected value for the IOP and to reclassify the type of glaucoma. Results: There was no significant difference in CCT between controls (552 ± 35 pro) and patients with POAG (543 ± 35 pro), but the CCT in the group with NTG (521 ± 31 μm) was significantly lower than that in the control group or the group with POAG (P