Abstract
Messenger RNA is a novel therapeutic modality which was key in curbing the Covid-19 pandemic. However, the delivery of mRNA in cells requires the development of smart vectors. We here report on amphiphilic dynamic covalent polymers formed in situ through RNA templating, and show effective nanoparticle formation and delivery of EGFP mRNA in cells.
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CITATION STYLE
APA
Coll, J. G., Ali, L. M. A., Montenegro, J., Bettache, N., & Ulrich, S. (2025). mRNA delivery with templated dynamic covalent polymers. Chemical Communications, 61(20), 4050–4053. https://doi.org/10.1039/d4cc06518b
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