Total phenolic, antioxidant activity and toxicity effect of Turbinaria decurrens extracts from South Sulawesi

Abstract

T.decurrens is a species of brown algae (Phaeophyta) that has bioactivity potential. This study aims to determine the total phenolic, antioxidant activity, and toxicity effects of n-hexane, ethyl acetate, and methanol extract. The effect of toxicity was carried out using the Artemia salina L death test method. Meanwhile, the antioxidant test uses the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and Folin Ciocalteu method is used for total phenolic content. The output of antioxidant activity of T. decurrens in ethyl acetate extract has an IC50 value of 180.54 μg/mL. Similar results have been found in the effects of toxicity and total phenolic content, which showed that ethyl acetate extracts gave LC50 values of 25.41 μg/mL, and total values of phenolic content of 4.8091 mg EAG/g, respectively. This indicated that ethyl acetate extract from T. decurrens has the potential as anticancer.